Baelorn said:
/PUP is a good solo option at really low levels for most melee jobs. At higher levels I've only heard of NIN/PUP working very well. For BLM solo the goal is really just to kill the mob before it kills you. Getting hit and the mob staying alive long enough for the auto to cure you really isn't much of an option. You also have to engage the auto for it to use cures which is a problem if you're sleeping the mob.
Not only that, but you lose the nice things in life (that is, keeping your life with Stoneskin, Blink, Phalanx or however you spell it, Reraise, added INT, added MP, Gravity, Bindability (no INT, no Bind)).
Not that I'm discouraging you to try it, but after tasting dirt several times, you might realize that the sub won't help much.
But in light of that, I just got to say this....